Vol. 18 | Vol. 18 (1) – January / February 2023 | SKIN CARE

Protective effects of skin barrier integrity against emotional stress, by an enriched Oat β-Glucan complex derived from Avena sativa L.

by cyb2025

EMILIE GOMBERT*, CARA DEWIS
*Corresponding author
Oat Cosmetics, Southampton, United Kingdom

ABSTRACT

The skin stress response is the activation of the endocrine, neurologic, and immune systems triggering a cascade of impacts. Cortisol is a stress hormone and prolonged exposure to elevated levels causes an increase in reactive oxygen species. Oat β-glucans have been reported to have beneficial effects on skin health.
This work presents evidence of the protective effects of an enriched Oat β-glucan complex on the skin barrier integrity against emotional stress and on the effectiveness of delaying the first signs of skin-ageing. Clinical studies show that this complex protects against stress-related skin damage. Due to its high anti-oxidation and stress-response upregulation in genes, stratum corneum integrity is maintained, stress-induced skin thinning is reduced, and skin smoothness is improved.

INTRODUCTION
Skin stress, results in multiple physiological impacts leading to a variety of skin disorders. A stress response is the activation of the endocrine, neurologic, and immune systems triggering a cascade of impacts, that are both systemic and cutaneous. Both the sympathetic nervous system and the hypothalamic-pituitary-adrenal system participate in the stress response (1). The consequential release of cortisol, catecholamines and neuropeptides have multiple clinical effects including an increase in skin inflammation, impaired skin barrier function, impaired wound healing, and suppressed immunity (2).

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