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Imperfectly perfect: moisturising and anti-ageing potential of an oil-soluble extract from rejected avocados

Avocado (Persea Americana) consumption has experienced a remarkably fast increase in demand, which inevitably leads to significant waste along the production chain. In recent years, the increased awareness of the environmental impact linked to food loss generated a huge rise in demand for sustainable goods. In this study we evaluated the moisturising effect, and the mechanisms behind it, of an oil-soluble extract from aesthetically imperfect, and thus rejected, avocado fruits cultivated in Sicily. Through in vitro and ex-vivo studies, we demonstrated that this new active ingredient significantly up-regulated proteins with key functions in the maintenance of intracellular water balance. Moreover, we showed that the extract promoted an overall improvement of epidermal barrier function by increasing the synthesis of lipid structures. Finally, clinical studies showed that the extract improved skin hydration and dermal density.

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Balancing the skin microbiome: fact or fiction

The “skin microbiome” consists of the skin’s resident microorganisms (bacteria, archaea, fungi, viruses) as well as their genomic content and metabolic by-products. Modern techniques for sequencing DNA have enabled researchers to find microbes that could not be cultured in the lab using traditional microbiology culture techniques. Skin microflora is influenced by environmental conditions, temperature, humidity, clothing, exposure to pollution as well as internal factors like diet and psychological stress, thus making it very challenging to study and understand. Nevertheless, the cosmetic industry is teeming with products claiming to “balance” the skin microbiome. There is no doubt that there is a serious shift in microbiome diversity of diseased skin versus healthy skin. However, healthy skin is balanced already, so claims to balance healthy skin with cosmetics is somewhat a fallacy.
Studies are needed to determine the variations in the day to day, week to week as well as seasonal and other environmental factors on healthy skin microbiome of untreated skin to determine if the changes observed from cosmetic products is meaningful.

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Turning consumer biases into added benefits with active ingredients

From conventional cosmetics to oral care and sexual wellbeing, the personal care industry is continuously expanding into the growing wellness and self-care space. In order to differentiate from other brands in an already crowded space, developers and marketers must find effective ways to connect with the consumer with products that have a real impact on consumer routines and lifestyles. Brands can address consumer priorities and interests with the inclusion of active ingredients to entice consumers and build confidence in buying decisions. Incorporating active ingredients into products to enhance the desired effect requires a favorable consumer perception to determine the true value of the additive. For a product with a commercialized active to be successful, brands must not only address the need but articulate and promote it in a way that consumers are familiar, driving not only the initial checkout but also future repurchases.

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To test or not to test – A very good question indeed!

When HPC Today invited me to contribute this article, I was delighted at the prospect, yet concerned that, yet again, the industry needs reminding that the requirement to support product claims. What is it then, that despite the global Cosmetic Regulations, notably our own here in the EU, Marketing, Copy writers, and even many in ‘R&D’ still don’t get when it comes to testing cosmetics to support product claims? Why does that very word ‘test’ cause stress among many in the industry? This article looks at the key reasons why; the body of evidence; the types of testing available, and their differences; how these differences impact on not only what claims you make, but also interpretation and business risk in its wider context.

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Natural astaxanthin – the red diamond amongst antioxidants – An efficient antioxidant that provides biological cell protection against light-induced skin damage

Exposure to solar radiation is a major cause of physiological skin damage by promoting the formation of free radicals and triggering oxidative stress. Harmful UV irradiation leads to inflammation, accelerated skin ageing and malignant skin disease. Therefore, we need to protect our outermost barrier from harmful solar radiation to reduce light-induced skin changes.
Astaxanthin, a naturally occurring reddish pigment derived from the microalga Haematococcus pluvialis, is considered the most powerful natural antioxidant with no pro-oxidant or phototoxic character, highly effective in counteracting reactive oxygen species (ROS).
Numerous studies have shown astaxanthin’s positive effect on human skin. Due to its high antioxidant and anti-inflammatory properties, it supports the skin’s oxidative balance, inhibits inflammatory processes and provides natural protection of the human skin against a negative impact of UV rays. Furthermore, astaxanthin supports the skin’s biological cell protection against light-induced damage without providing a sun protection factor (SPF).

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Biotic ingredients with a proven skin anti-aging effect – Two active ingredients based on Lactobacillus crispatus that help reduce the signs of skin aging

Demand for anti-aging cosmetic products is thriving – consumers are increasingly interested in healthy aging and natural safe ingredients. In this context, biotic ingredients are gaining popularity because they are associated with health, wellness and eco-friendliness. Two new biotic ingredients based on the Lactobacillus crispatus bacteria are now enabling cosmetics producers to respond to this trend. These solutions are among the first biotic ingredients derived from bacteria that are naturally present on the skin, and which decrease with aging. When applied onto the skin, the two specific Lactobacillus crispatus derived actives provide clinically proven antiaging benefits.

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Fatty acids – Biological and cosmetic raw materials

Fatty acids and triglycerides make up a wide class of compounds that are vitally important in biological systems, they also find applications in personal care formulations. There is a particular interest in fatty acid esters and triglycerides that are liquid at ambient temperatures. The proper selection of fatty acids to make triglycerides and esters will allow for the cushion and play time in a personal care formulation that consumers require. The most common class of fatty acids is saturated fatty acids, which are solid at room temperature, excluding short chain fatty acids, C8 and below.
An approach to get liquid esters and triglycerides is to choose fatty acids that are either unsaturated, branched, or short chain fatty acids, such as C10 or C8 in Caprylic/Capric Triglycerides This article will look at the various classes of fatty acids comparing the various types to each other. Additionally, a series of fatty acids produced by bacteria having a unique structure will be introduced.

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